Frontiers | Induction of Cross-Reactive and Protective

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Specificity and complexity at the level of receptors. The mechanisms of receptor activation have been intensively studied through the analysis of receptor tyrosine kinases (RTKs), which possess a single membrane-spanning region, and related multisubunit receptors, such as those for cytokines and antigens that signal through associated cytoplasmic tyrosine kinases (Hunter 2000). ...read more

 

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2/2/2016 · AUTHORS Keith S. Taber 1 Richard Brock 1 Gabriela Martínez Sainz 1 1 Faculty of Education, University of Cambridge ABSTRACT This article explores the value and potential challenges of supervisor-student co-writing during a research degree programme. The article comprises of (i) a text prepared by a faculty research supervisor (KST) arguing the case for encouraging… ...read more

 

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2/27/2017 · Understanding the loss of conserved genes is critical for determining how phenotypic diversity is generated. Here we focus on the evolution of DCC, a gene that encodes a highly conserved neural ...read more

 

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6/20/2017 · Suitable chemical tools have been instrumental in the discovery and characterization of the endocannabinoid system. However, the lack of potent and selective inhibitors for endocannabinoid transport has prevented the molecular characterization of this process. Current uptake inhibitors are poorly bioavailable to the central nervous system (CNS) and weakly selective because they also inhibit ...read more

 

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Melanoma cells can switch between an elongated mesenchymal-type and a rounded amoeboid-type migration mode. The rounded ‘amoeboid’ form of cell movement is driven by actomyosin contractility resulting in membrane blebbing. Unlike elongated A375 melanoma cells, rounded A375 cells do not display any obvious morphological front–back polarisation, although polarisation is thought to be a ...read more

 

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Generally, natural mRNA has a single strand structure, consisting of. a 7-methyl-guanosine residue binding at the 5’-end (the 5’-cap) and a. poly (A)-tail at the 3’-end. The protein encoding ...read more

 

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quality fuels is measured as electricity use per capita up to a threshold level. Ahlen (2004) shows that a close statistical relationship exists between human welfare and electricity consumption per capita. Reliability is not yet captured in a single metric. In this paper we focus on the indicators of SED defined by Davidsdottir et al (2007) to ...read more

 

Cancer-Specific Synthetic Lethality between ATR and CHK1

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Regulation of Salmonella enterica Pathogenicity Island 1

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(PDF) The challenge and prospect of mRNA therapeutics

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Immediate Provisionalization and Nonfunctional Loading of

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Top 10 Sci-Fi Films of the 1920s – scifist 2.0

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Chemical probes to potently and selectively inhibit

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In 2016, a novel interrogation technique for phase-sensitive (Φ)OTDR was mathematically formalized and experimentally demonstrated, based on the use of a chirped-pulse as a probe, in an otherwise direct-detection-based standard setup: chirped-pulse (CP-)ΦOTDR. Despite its short lifetime, this methodology has now become a reference for distributed acoustic sensing (DAS) due to its ...read more